Job Advertisement HKI-04/2021

The Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute – (HKI, www.leibniz-hki.de) investigates the pathobiology of human-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The department Bio Pilot Plant invites talented and highly gifted candidates to apply as a

Doctoral Researcher (f/div/m) in Microbial Physiology / Electrochemistry

Research Areas:

The Bio Pilot Plant is focused on elucidating and utilizing microbial interactions with electrochemical systems to develop new strategies for target microbial bioprocesses. Within the DFG funded Priority Program 2240 “eBiotech”, a collaboration project with the research group of Prof. Falk Harnisch (UFZ Leipzig) will be initiated for the development of an integrated anaerobic electrobioreactor for bacteria consuming electrons from a cathode. While a co-worker from the Harnisch group will focus on reactor engineering, we seek a talented PhD student who will focus on evaluating the performance of the bacteria for microbial electrochemical synthesis (MES) compared to classical cultivations.

The successful candidate will design and develop experiments with two different obligate anaerobic, cathodic bacteria to evaluate the impact of cathodic and anodic function on microbial performance. Methods will involve deep physiological characterizations of metabolic activity and stress response (e.g., with transcriptome and proteome analysis). Work will take place in a dynamic and highly motivated group. Within the group, the PhD student will experience a strong support based on lively collaboration and friendly interaction between the interdisciplinary scientists and access to state-of-the-art equipment. A very tight and integrated collaboration with the Harnisch group (1 hour travel distance) is essential in this project. In addition, the applicant will intensively engage in the PhD student network of the new Priority Program with two dozen research projects in the area of bioelectrochemistry.

Main Requirements:
  • Master´s degree (or equivalent) in microbiology, biochemistry, microbial physiology, metabolic engineering or related disciplines
  • Favorably with basic knowledge of electrochemistry
  • Mandatory experience in microbial pure culture cultivations, ideally even with anaerobic bacteria
  • Strong knowledge in analytical techniques to investigate microbial physiology (e.g., transcriptomics and/or proteomics)
  • The candidate should embrace working in an international, interdisciplinary research team
  • Ability for team-oriented as well as creative and independent work
  • Very good communication and reporting skills in English

Preferred Skills:

  • Experience in microbial electrochemistry and/or bioprocess engineering would be an advantage
  • Advanced knowledge in metabolic engineering especially of bacteria

We offer:

The successful candidate will be hosted in the department Bio Pilot Plant headed by Prof. Dr. Miriam Agler-Rosenbaum. The group conducts innovative cutting-edge research by combining synthetic biology with natural product research and infection biology. The Leibniz-HKI is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-the-art research facilities and a highly integrative network of life science groups. We offer a multifaceted scientific project supported by excellent technical facilities, a place in a young, committed team, as well as strong scientific collaborations. The PhD candidate will participate in the structured program of the International Leibniz Research School and become an associated member of the Jena School of Microbial Communication.

Salary is paid according to German TV-L (salary agreement for public service employees). As an equal opportunity employer the Leibniz-HKI is committed to increase the percentage of female scientists and therefore especially encourages them to apply.
 

For further information:

Prof. Miriam Rosenbaum | +49 3641 532 1120 | career@leibniz-hki.de

Applications:

Complete applications in English or German should include a letter of interest, curriculum vitae, a complete list of publications, brief statement of research experiences, a list of three potential references, full academic record (copies of degree certificates), and should be submitted by February 28, 2021, via the online application system.